Yes sir, all that is part of the calibration process. I used to help build the ECU's for Honda... they take no shortcuts in engineering.Not sure how the octane level would affect the engine at high altitudes, heat, etc but I assume HOnda took everything into account when testing the new civic so it wouldn't run into these problems.
I worked for Keihin (Honda subsidiary) from 2005 - 2009. The calibration process is carried out in a controlled lab environment, with subsequent testing done in extreme conditions on a test track, then the camouflaged versions we see in the sneek peeks from different locations. I was involved only with the manufacturing side of the ECU's. From my observations and experiences, Honda takes no shortcuts in their engineering.Did Honda bring prototypes to high altitudes for testing? Did you get to go with the prototypes to make sure the ECU is adjusting the actuators properly?